Immunologic Risk Factors for Early Mortality After Starting Antiretroviral Therapy in HIV-Infected Zambian Children
نویسندگان
چکیده
منابع مشابه
Early mortality and loss to follow-up in HIV-infected children starting antiretroviral therapy in Southern Africa.
BACKGROUND Many HIV-infected children in Southern Africa have been started on antiretroviral therapy (ART), but loss to follow up (LTFU) can be substantial. We analyzed mortality in children retained in care and in all children starting ART, taking LTFU into account. PATIENTS AND METHODS Children who started ART before the age of 16 years in 10 ART programs in South Africa, Malawi, Mozambique...
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BACKGROUND There are limited data of immunologic and virologic failure in Asian HIV-infected children using non-nucleoside reverse transcriptase inhibitor (NNRTI)-based highly active antiretroviral therapy (HAART). We examined the incidence rate of immunologic failure (IF) and virologic failure (VF) and the accuracy of using IF to predict VF in Thai HIV-infected children using first-line NNRTI-...
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BACKGROUND A substantial proportion of HIV-infected adults starting antiretroviral therapy (ART) in sub-Saharan Africa are malnourished. We aimed to increase understanding of the factors affecting their high mortality, particularly in the high-risk period before ART initiation. METHODS We analysed potential risk factors for mortality of Zambian and Tanzanian participants enrolled in the NUSTA...
متن کاملThe impact of daily cotrimoxazole prophylaxis and antiretroviral therapy on mortality and hospital admissions in HIV-infected Zambian children.
BACKGROUND Data on the population effectiveness of cotrimoxazole prophylaxis and antiretroviral therapy (ART) in human immunodeficiency virus (HIV)-infected African children are few. METHODS A total of 534 Zambian children with HIV infection were randomized to receive daily cotrimoxazole prophylaxis or placebo in the Children with HIV Antibiotic Prophylaxis trial. Following trial closure, chi...
متن کاملPredictors of mortality in HIV-infected patients starting antiretroviral therapy in a rural hospital in Tanzania
BACKGROUND Studies of antiretroviral therapy (ART) programs in Africa have shown high initial mortality. Factors contributing to this high mortality are poorly described. The aim of the present study was to assess mortality and to identify predictors of mortality in HIV-infected patients starting ART in a rural hospital in Tanzania. METHODS This was a cohort study of 320 treatment-naïve adult...
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ژورنال
عنوان ژورنال: AIDS Research and Human Retroviruses
سال: 2013
ISSN: 0889-2229,1931-8405
DOI: 10.1089/aid.2012.0246